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Site-selective (1)H/(2)H labeling enables artifact-free (1)H CPMG relaxation dispersion experiments in aromatic side chains

Aromatic side chains are often key residues in enzyme active sites and protein binding sites, making them attractive probes of protein dynamics on the millisecond timescale. Such dynamic processes can be studied by aromatic (13)C or (1)H CPMG relaxation dispersion experiments. Aromatic (1)H CPMG rel...

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Bibliografiska uppgifter
I publikationen:J Biomol NMR
Huvudupphovsmän: Raum, Heiner N., Schörghuber, Julia, Dreydoppel, Matthias, Lichtenecker, Roman J., Weininger, Ulrich
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Netherlands 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859156/
https://ncbi.nlm.nih.gov/pubmed/31506857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-019-00275-z
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