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Site-selective (1)H/(2)H labeling enables artifact-free (1)H CPMG relaxation dispersion experiments in aromatic side chains

Aromatic side chains are often key residues in enzyme active sites and protein binding sites, making them attractive probes of protein dynamics on the millisecond timescale. Such dynamic processes can be studied by aromatic (13)C or (1)H CPMG relaxation dispersion experiments. Aromatic (1)H CPMG rel...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biomol NMR
Prif Awduron: Raum, Heiner N., Schörghuber, Julia, Dreydoppel, Matthias, Lichtenecker, Roman J., Weininger, Ulrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Netherlands 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859156/
https://ncbi.nlm.nih.gov/pubmed/31506857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-019-00275-z
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