Locally instructed CXCR4(hi) neutrophils trigger environment-driven allergic asthma through the release of neutrophil extracellular traps

Low exposure to microbial products, respiratory viral infections and air pollution is a major risk factor for allergic asthma, yet the mechanistic links between such conditions and host susceptibility to type 2 allergic disorders remain unclear. Through the use of single-cell RNA sequencing (scRNA-s...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Radermecker, Coraline, Sabatel, Catherine, Vanwinge, Céline, Ruscitti, Cecilia, Maréchal, Pauline, Perin, Fabienne, Schyns, Joey, Rocks, Natacha, Toussaint, Marie, Cataldo, Didier, Johnston, Sebastian L, Bureau, Fabrice, Marichal, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859073/
https://ncbi.nlm.nih.gov/pubmed/31591573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0496-9
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