House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation

Allergic skin diseases, such as atopic dermatitis (AD), are clinically characterized by severe itching and type 2 immunity-associated hypersensitivity to widely-distributed allergens, including those derived from house dust mites (HDMs). Here we found that HDMs with cysteine-protease activity direct...

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Pubblicato in:Nat Immunol
Autori principali: Serhan, Nadine, Basso, Lilian, Sibilano, Riccardo, Petitfils, Camille, Meixiong, James, Bonnart, Chrystelle, Reber, Laurent L., Marichal, Thomas, Starkl, Philipp, Cenac, Nicolas, Dong, Xinzhong, Tsai, Mindy, Galli, Stephen J., Gaudenzio, Nicolas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858877/
https://ncbi.nlm.nih.gov/pubmed/31591569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0493-z
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