Φορτώνει......
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion
A rare loss-of-function allele p.Arg138* in SLC30A8 encoding the zinc transporter 8 (ZnT8), enriched in Western Finland, protects against type 2 diabetes (T2D). We recruited relatives of the identified carriers and showed that protection was associated with better insulin secretion due to enhanced g...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Genet |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6858874/ https://ncbi.nlm.nih.gov/pubmed/31676859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0513-9 |
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