Safety, pharmacokinetics and pharmacodynamics of the selective glucocorticoid receptor modulator AZD7594, following inhalation in healthy Japanese volunteers

INTRODUCTION: AZD7594 is a non-steroidal, selective, glucocorticoid receptor modulator (SGRM), currently in development for the treatment of asthma and chronic obstructive pulmonary disease. This paper reports a randomized placebo-controlled dose escalation study in healthy Japanese male subjects. M...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Prothon, Susanne, Wählby Hamrén, Ulrika, Tehler, Ulrika, Yoon, Esther, Forsman, Henrik, Arfvidsson, Cecilia, Aggarwal, Ajay, Chen, Yingxue
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858834/
https://ncbi.nlm.nih.gov/pubmed/31814707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S215170
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