Highly versatile cancer photoimmunotherapy using photosensitizer-conjugated avidin and biotin-conjugated targeting antibodies

BACKGROUND: Photoimmunotherapy (PIT) employing antibody-photosensitizer conjugates is a promising treatment for cancer. However, the fixed antigen specificity severely limits the efficacy and the applicability. Here we describe a universal strategy for PIT of cancer by using a near-infrared (NIR) ph...

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Vydáno v:Cancer Cell Int
Hlavní autoři: Shirasu, Naoto, Shibaguchi, Hirotomo, Yamada, Hiromi, Kuroki, Masahide, Yasunaga, Shin’ichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Primary Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858743/
https://ncbi.nlm.nih.gov/pubmed/31787847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-1034-4
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