Histological, immunohistochemical and mRNA gene expression responses in coeliac disease patients challenged with gluten using PAXgene fixed paraffin-embedded duodenal biopsies

BACKGROUND: There is an unmet need for novel treatments, such as drugs or vaccines, adjunctive to or replacing a burdensome life-long gluten-free diet for coeliac disease. The gold standard for successful treatment is a healed small intestinal mucosa, and therefore, the outcome measures in proof-of-...

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Vydáno v:BMC Gastroenterol
Hlavní autoři: Taavela, Juha, Viiri, Keijo, Popp, Alina, Oittinen, Mikko, Dotsenko, Valeriia, Peräaho, Markku, Staff, Synnöve, Sarin, Jani, Leon, Francisco, Mäki, Markku, Isola, Jorma
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858741/
https://ncbi.nlm.nih.gov/pubmed/31730447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-019-1089-7
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