Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits

Volumetric variations of human brain are heritable and are associated with many brain-related complex traits. Here we performed genome-wide association studies (GWAS) of 101 brain volumetric phenotypes using the UK Biobank (UKB) sample including 19,629 participants. GWAS identified 365 independent g...

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Veröffentlicht in:Nat Genet
Hauptverfasser: Zhao, Bingxin, Luo, Tianyou, Li, Tengfei, Li, Yun, Zhang, Jingwen, Shan, Yue, Wang, Xifeng, Yang, Liuqing, Zhou, Fan, Zhu, Ziliang, Zhu, Hongtu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858580/
https://ncbi.nlm.nih.gov/pubmed/31676860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0516-6
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