Pan-viral serology implicates enteroviruses in acute flaccid myelitis

Since 2012, the United States has experienced a biennial spike in pediatric acute flaccid myelitis (AFM).(1–6) Epidemiologic evidence suggests non-polio enteroviruses (EVs) are a potential etiology, yet EV RNA is rarely detected in cerebrospinal fluid (CSF).(2) We interrogated CSF from children with...

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Publicado no:Nat Med
Main Authors: Schubert, Ryan D., Hawes, Isobel A., Ramachandran, Prashanth S., Ramesh, Akshaya, Crawford, Emily D., Pak, John E., Wu, Wesley, Cheung, Carly K., O’Donovan, Brian D., Tato, Cristina M., Lyden, Amy, Tan, Michelle, Sit, Rene, Sowa, Gavin A., Sample, Hannah A., Zorn, Kelsey C., Banerji, Debarko, Khan, Lillian M., Bove, Riley, Hauser, Stephen L., Gelfand, Amy A., Johnson-Kerner, Bethany, Nash, Kendall, Krishnamoorthy, Kalpathy S., Chitnis, Tanuja, Ding, Joy Z., McMillan, Hugh J., Chiu, Charles Y., Briggs, Benjamin, Glaser, Carol A., Yen, Cynthia, Chu, Victoria, Wadford, Debra A., Dominguez, Samuel R., Fei Fan Ng, Terry, Marine, Rachel L., Lopez, Adriana S., Nix, W. Allan, Soldatos, Ariane, Gorman, Mark P., Benson, Leslie, Messacar, Kevin, Konopka-Anstadt, Jennifer L., Oberste, M. Steven, DeRisi, Joseph L., Wilson, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858576/
https://ncbi.nlm.nih.gov/pubmed/31636453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-019-0613-1
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