Dual Roles of mTOR in Regulating Liver Injury and Tumorigenesis in Autophagy Defective Mouse Liver

Autophagy is a lysosomal degradation pathway that degrades cytoplasmic proteins and organelles. Absence of autophagy in hepatocytes has been linked to promoting liver injury and tumorigenesis, however the mechanisms behind why a lack of autophagy induces these complications is not fully understood....

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Publicado en:Hepatology
Autores principales: Ni, Hong-Min, Chao, Xiaojuan, Yang, Hua, Deng, Fengyan, Wang, Shaogui, Bai, Qingyun, Qian, Hui, Cui, Yue, Cui, Wei, Shi, Yinghong, Zong, Wei-Xing, Wang, Zhengtao, Yang, Li, Ding, Wen-Xing
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858484/
https://ncbi.nlm.nih.gov/pubmed/31095752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30770
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