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Implementation of interference reflection microscopy for label-free, high-speed imaging of microtubules

There are several methods for visualizing purified biomolecules near surfaces. Total-internal reflection fluorescence (TIRF) microscopy is a commonly used method, but has the drawback that it requires fluorescent labeling, which can interfere with the activity of the molecules. Also, photobleaching...

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Publicat a:J Vis Exp
Autors principals: Mahamdeh, Mohammed, Howard, Jonathon
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858481/
https://ncbi.nlm.nih.gov/pubmed/31449260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/59520
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