Modular actin nano-architecture enables podosome protrusion and mechanosensing

Basement membrane transmigration during embryonal development, tissue homeostasis and tumor invasion relies on invadosomes, a collective term for invadopodia and podosomes. An adequate structural framework for this process is still missing. Here, we reveal the modular actin nano-architecture that en...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: van den Dries, Koen, Nahidiazar, Leila, Slotman, Johan A., Meddens, Marjolein B. M., Pandzic, Elvis, Joosten, Ben, Ansems, Marleen, Schouwstra, Joost, Meijer, Anke, Steen, Raymond, Wijers, Mietske, Fransen, Jack, Houtsmuller, Adriaan B., Wiseman, Paul W., Jalink, Kees, Cambi, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858452/
https://ncbi.nlm.nih.gov/pubmed/31729386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13123-3
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