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A rationale for surgical debulking to improve anti-PD1 therapy outcome in non small cell lung cancer

Anti-PD1 immunotherapy has emerged as a gold-standard treatment for first- or second-line treatment of stage IV NSCLC, with response rates ranging from 10 to 60%. Strategies to improve the disease control rate are needed. Several reports suggested that debulking surgery enhances anti-tumor immunity....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Guisier, Florian, Cousse, Stephanie, Jeanvoine, Mathilde, Thiberville, Luc, Salaun, Mathieu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858444/
https://ncbi.nlm.nih.gov/pubmed/31729430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52913-z
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