Reciprocal interactions between mtDNA and lifespan control in budding yeast

Loss of mitochondrial DNA (mtDNA) results in loss of mitochondrial respiratory activity, checkpoint-regulated inhibition of cell cycle progression, defects in growth, and nuclear genome instability. However, after several generations, yeast cells can adapt to the loss of mtDNA. During this adaptatio...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Garcia, Enrique J., de Jonge, Janeska J., Liao, Pin-Chao, Stivison, Elizabeth, Sing, Cierra N., Higuchi-Sanabria, Ryo, Boldogh, Istvan R., Pon, Liza A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2019
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857569/
https://ncbi.nlm.nih.gov/pubmed/31599702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-06-0356
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