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Cellular source of hypothalamic macrophage accumulation in diet-induced obesity

BACKGROUND: Obese mice on a high-fat diet (HFD) display signs of inflammation in the hypothalamic arcuate nucleus (ARC), a critical area for controlling systemic energy metabolism. This has been suggested as a key mechanism of obesity-associated hypothalamic dysfunction. We reported earlier that bon...

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Foilsithe in:J Neuroinflammation
Main Authors: Lee, Chan Hee, Shin, Sung Hoon, Kang, Gil Myoung, Kim, Seongjun, Kim, Jiye, Yu, Rina, Kim, Min-Seon
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857282/
https://ncbi.nlm.nih.gov/pubmed/31727092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1607-0
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