Targeting of tolerogenic dendritic cells to heat-shock proteins in inflammatory arthritis

BACKGROUND: Autologous tolerogenic dendritic cells (tolDC) are a promising therapeutic strategy for inflammatory arthritis (IA) as they can regulate autoantigen-specific T cell responses. Here, we investigated two outstanding priorities for clinical development: (i) the suitability of using heat-sho...

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Dettagli Bibliografici
Pubblicato in:J Transl Med
Autori principali: Spiering, Rachel, Jansen, Manon A. A., Wood, Matthew J., Fath, Anshorulloh A., Eltherington, Oliver, Anderson, Amy E., Pratt, Arthur G., van Eden, Willem, Isaacs, John D., Broere, Femke, Hilkens, Catharien M. U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857208/
https://ncbi.nlm.nih.gov/pubmed/31727095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-2128-4
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