The novel GINS4 axis promotes gastric cancer growth and progression by activating Rac1 and CDC42

Rationale: As a component of GINS complex, GINS4 is essential for initiating DNA replication and elongation of the cell cycle G1/S phase in eukaryotes and plays a vital role in normal physiological processes. However, the precise functions and regulation mechanisms of GINS4 in human tumors remain el...

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Bibliographic Details
Published in:Theranostics
Main Authors: Zhu, Zhonglin, Yu, Zhilong, Rong, Zeyin, Luo, Zai, Zhang, Jing, Qiu, Zhengjun, Huang, Chen
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2019
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857050/
https://ncbi.nlm.nih.gov/pubmed/31754397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.36256
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