Large-scale PRNP genotyping of small ruminants using an automated high-throughput MALDI-TOF MS assay

Scrapie resistance or susceptibility in sheep is associated with single nucleotide polymorphisms (SNPs) at codons 136, 154, and 171 of the prion protein gene (PRNP). In addition, phenylalanine mutation at codon 141 has been recognized as a risk factor for atypical scrapie. In contrast, K222, D146, a...

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Detalhes bibliográficos
Publicado no:J Vet Diagn Invest
Main Authors: Migliore, Sergio, Bivona, Maurizio, Gagliostro, Enrico, Buttitta, Onofrio, Lo Mascolo, Francesca, Macrì, Daniele
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857025/
https://ncbi.nlm.nih.gov/pubmed/31238800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1040638719859043
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