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A pilot study of peripheral blood DNA methylation models as predictors of knee osteoarthritis radiographic progression: data from the Osteoarthritis Initiative (OAI)

Knee osteoarthritis (OA) is a leading cause of chronic disability worldwide, but no diagnostic or prognostic biomarkers are available. Increasing evidence supports epigenetic dysregulation as a contributor to OA pathogenesis. In this pilot study, we investigated epigenetic patterns in peripheral blo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: M. Dunn, Christopher, Nevitt, Michael C., Lynch, John A., Jeffries, Matlock A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856188/
https://ncbi.nlm.nih.gov/pubmed/31727952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53298-9
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