A human expression system based on HEK293 for the stable production of recombinant erythropoietin

Mammalian host cell lines are the preferred expression systems for the manufacture of complex therapeutics and recombinant proteins. However, the most utilized mammalian host systems, namely Chinese hamster ovary (CHO), Sp2/0 and NS0 mouse myeloma cells, can produce glycoproteins with non-human glyc...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chin, Christine Lin, Goh, Justin Bryan, Srinivasan, Harini, Liu, Kaiwen Ivy, Gowher, Ali, Shanmugam, Raghuvaran, Lim, Hsueh Lee, Choo, Matthew, Tang, Wen Qin, Tan, Andy Hee-Meng, Nguyen-Khuong, Terry, Tan, Meng How, Ng, Say Kong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856173/
https://ncbi.nlm.nih.gov/pubmed/31727983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53391-z
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