Disrupting coupling within mycobacterial F-ATP synthases subunit ε causes dysregulated energy production and cell wall biosynthesis

The dynamic interaction of the N- and C-terminal domains of mycobacterial F-ATP synthase subunit ε is proposed to contribute to efficient coupling of H(+)-translocation and ATP synthesis. Here, we investigate crosstalk between both subunit ε domains by introducing chromosomal atpC missense mutations...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Saw, Wuan-Geok, Wu, Mu-Lu, Ragunathan, Priya, Biuković, Goran, Lau, Aik-Meng, Shin, Joon, Harikishore, Amaravadhi, Cheung, Chen-Yi, Hards, Kiel, Sarathy, Jickky Palmae, Bates, Roderick W., Cook, Gregory M., Dick, Thomas, Grüber, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856130/
https://ncbi.nlm.nih.gov/pubmed/31727946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53107-3
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