In vitro Activity and Heteroresistance of Omadacycline Against Clinical Staphylococcus aureus Isolates From China Reveal the Impact of Omadacycline Susceptibility by Branched-Chain Amino Acid Transport System II Carrier Protein, Na/Pi Cotransporter Family Protein, and Fibronectin-Binding Protein

Omadacycline (Omad), a new tetracycline (Tet)-class broad-spectrum aminomethylcycline, has been reported to exhibit excellent potency against Gram-positive bacteria, including Staphylococcus aureus and Enterococci. The aim of this study was to evaluate the in vitro activity and heteroresistance char...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Bai, Bing, Lin, Zhiwei, Pu, Zhangya, Xu, Guangjian, Zhang, Fan, Chen, Zhong, Sun, Xiang, Zheng, Jinxin, Li, Peiyu, Deng, Qiwen, Yu, Zhijian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856048/
https://ncbi.nlm.nih.gov/pubmed/31787948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02546
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