P2Y6 and P2X7 Receptor Antagonism Exerts Neuroprotective/ Neuroregenerative Effects in an Animal Model of Parkinson’s Disease

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by decreased dopamine bioavailability in the substantia nigra and the striatum. Taking into account that adenosine-5’-triphosphate (ATP) and its metabolites are intensely released in the 6-hydroxydopamine (6-OHDA) animal model of...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Oliveira-Giacomelli, Ágatha, M. Albino, Carolina, de Souza, Hellio Danny Nóbrega, Corrêa-Velloso, Juliana, de Jesus Santos, Ana Paula, Baranova, Juliana, Ulrich, Henning
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Cellular Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856016/
https://ncbi.nlm.nih.gov/pubmed/31787881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00476
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