TP53 Status as a Determinant of Pro- vs Anti-Tumorigenic Effects of Estrogen Receptor-Beta in Breast Cancer

BACKGROUND: Anti-tumorigenic vs pro-tumorigenic roles of estrogen receptor-beta (ESR2) in breast cancer remain unsettled. We investigated the potential of TP53 status to be a determinant of the bi-faceted role of ESR2 and associated therapeutic implications for triple negative breast cancer (TNBC)....

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Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Mukhopadhyay, Utpal K, Oturkar, Chetan C, Adams, Christina, Wickramasekera, Nadi, Bansal, Sanjay, Medisetty, Rajesh, Miller, Austin, Swetzig, Wendy M, Silwal-Pandit, Laxmi, Børresen-Dale, Anne-Lise, Creighton, Chad J, Park, Jun Hyoung, Konduri, Santhi D, Mukhopadhyay, Alka, Caradori, Alexander, Omilian, Angela, Bshara, Wiam, Kaipparettu, Benny Abraham, Das, Gokul M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855950/
https://ncbi.nlm.nih.gov/pubmed/30990221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djz051
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