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Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells: An integrative approach using high-throughput datasets

Gene expression governs cell fate, and is regulated via a complex interplay of transcription factors and molecules that change chromatin structure. Advances in sequencing-based assays have enabled investigation of these processes genome-wide, leading to large datasets that combine information on the...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Vijayabaskar, M. S., Goode, Debbie K., Obier, Nadine, Lichtinger, Monika, Emmett, Amber M. L., Abidin, Fatin N. Zainul, Shar, Nisar, Hannah, Rebecca, Assi, Salam A., Lie-A-Ling, Michael, Gottgens, Berthold, Lacaud, Georges, Kouskoff, Valerie, Bonifer, Constanze, Westhead, David R.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855567/
https://ncbi.nlm.nih.gov/pubmed/31682597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007337
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