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Genotype-matched Newcastle disease virus vaccine confers improved protection against genotype XII challenge: The importance of cytoplasmic tails in viral replication and vaccine design

Although typical Newcastle disease virus (NDV) vaccines can prevent mortality, they are not effective in preventing viral shedding. To overcome this, genotype-matched vaccines have been proposed. To date, this approach has never been tested against genotype XII strains. In this study, we generated a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Izquierdo-Lara, Ray, Chumbe, Ana, Calderón, Katherine, Fernández-Díaz, Manolo, Vakharia, Vikram N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855454/
https://ncbi.nlm.nih.gov/pubmed/31725727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209539
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