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Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids

The engineered AAV-PHP.B family of adeno-associated virus efficiently delivers genes throughout the mouse central nervous system. To guide their application across disease models, and to inspire the development of translational gene therapy vectors for targeting neurological diseases in humans, we s...

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書目詳細資料
發表在:PLoS One
Main Authors: Huang, Qin, Chan, Ken Y., Tobey, Isabelle G., Chan, Yujia Alina, Poterba, Tim, Boutros, Christine L., Balazs, Alejandro B., Daneman, Richard, Bloom, Jonathan M., Seed, Cotton, Deverman, Benjamin E.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855452/
https://ncbi.nlm.nih.gov/pubmed/31725765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225206
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