Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids

The engineered AAV-PHP.B family of adeno-associated virus efficiently delivers genes throughout the mouse central nervous system. To guide their application across disease models, and to inspire the development of translational gene therapy vectors for targeting neurological diseases in humans, we s...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Huang, Qin, Chan, Ken Y., Tobey, Isabelle G., Chan, Yujia Alina, Poterba, Tim, Boutros, Christine L., Balazs, Alejandro B., Daneman, Richard, Bloom, Jonathan M., Seed, Cotton, Deverman, Benjamin E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855452/
https://ncbi.nlm.nih.gov/pubmed/31725765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225206
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados