Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and latency

Sustained phosphotinositide3-kinase (PI3K) signaling is critical to the maintenance of alpha and beta herpesvirus latency. We have previously shown that the beta-herpesvirus, human cytomegalovirus (CMV), regulates epidermal growth factor receptor (EGFR), upstream of PI3K, to control states of latenc...

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Vydáno v:PLoS Pathog
Hlavní autoři: Buehler, Jason, Carpenter, Ethan, Zeltzer, Sebastian, Igarashi, Suzu, Rak, Michael, Mikell, Iliyana, Nelson, Jay A., Goodrum, Felicia
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855412/
https://ncbi.nlm.nih.gov/pubmed/31725811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008037
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