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Modulator role of infliximab and methotrexate through the transient receptor potential melastatin 2 (TRPM2) channel in neutrophils of patients with rheumatoid arthritis: a pilot study

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic, systemic, inflammatory disease causing symmetric polyarthritis. In this study, we aimed to investigate the effects of infliximab (INF) and methotrexate (MTX) on apoptosis, oxidative stress, and calcium signaling in the neutrophils of RA patients....

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Pubblicato in:Arch Med Sci
Autori principali: Dogru, Atalay, Nazıroglu, Mustafa, Cig, Bilal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Termedia Publishing House 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855169/
https://ncbi.nlm.nih.gov/pubmed/31749869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2018.79485
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