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Aldosterone nongenomically induces angiotensin II receptor dimerization in rat kidney: role of mineralocorticoid receptor and NADPH oxidase

INTRODUCTION: Previous in vitro studies demonstrated that aldosterone nongenomically induces transglutaminase (TG) and reactive oxygen species (ROS), which enhanced angiotensin II receptor (ATR) dimerization. There are no in vivo data in the kidney. MATERIAL AND METHODS: Male Wistar rats were intrap...

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Détails bibliographiques
Publié dans:Arch Med Sci
Auteurs principaux: Sinphitukkul, Kittisak, Manotham, Krissanapong, Eiam-Ong, Somchai, Eiam-Ong, Somchit
Format: Artigo
Langue:Inglês
Publié: Termedia Publishing House 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855162/
https://ncbi.nlm.nih.gov/pubmed/31749889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2019.87135
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