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miR-21 regulates vascular smooth muscle cell function in arteriosclerosis obliterans of lower extremities through AKT and ERK1/2 pathways

INTRODUCTION: Arteriosclerosis obliterans (ASO) is a disease that affects the lower extremities. The mechanism of ASO is associated with the proliferation and migration of vascular smooth muscle cells (VSMCs). miR-21 plays a key role in various biological processes of the cardiovascular system, asso...

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Опубликовано в: :Arch Med Sci
Главные авторы: Huang, Shuichuan, Xu, Tuo, Huang, Xianying, Li, Siyi, Qin, Wenyi, Chen, Weijie, Zhang, Zhi
Формат: Artigo
Язык:Inglês
Опубликовано: Termedia Publishing House 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855157/
https://ncbi.nlm.nih.gov/pubmed/31749878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2018.78885
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