Melatonin Reduces Androgen Production and Upregulates Heme Oxygenase-1 Expression in Granulosa Cells from PCOS Patients with Hypoestrogenia and Hyperandrogenia

BACKGROUND/AIMS: Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by abnormal hormone levels in peripheral blood and poor-quality oocytes. PCOS is a pathophysiological syndrome caused by chronic inflammation and oxidative stress. The aim of this study was to investigate the me...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Yu, Kun, Wang, Rong-Xiang, Li, Meng-Hui, Sun, Tie-Cheng, Zhou, Yi-Wen, Li, Yuan-Yuan, Sun, Li-Hua, Zhang, Bao-Lu, Lian, Zheng-Xing, Xue, Song-Guo, Liu, Yi-Xun, Deng, Shou-Long
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854986/
https://ncbi.nlm.nih.gov/pubmed/31772710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8218650
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