METTL3 Attenuates LPS-Induced Inflammatory Response in Macrophages via NF-κB Signaling Pathway

Methyltransferase-like 3 (METTL3), an RNA N(6)-methyladenosine (m(6)A) methyltransferase, is essential for the m(6)A mRNA modification. As a key enzyme of m(6)A methylation modification, METTL3 has been implicated in immune and inflammation regulation. However, little is known of the role and underl...

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Veröffentlicht in:Mediators Inflamm
Hauptverfasser: Wang, Jinghua, Yan, Shushan, Lu, Hongying, Wang, Shufeng, Xu, Donghua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854952/
https://ncbi.nlm.nih.gov/pubmed/31772500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3120391
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