The use of electron microscopy in the diagnosis of focal segmental glomerulosclerosis: are current pathological techniques missing important abnormalities in the glomerular basement membrane?

Background: There is an increasing appreciation that variants of the COL4A genes may be associated with the development of focal segmental glomerulosclerosis (FSGS). On electron microscopy, such variants may produce characteristic changes within the glomerular basement membrane (GBM). These changes...

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Publicat a:F1000Res
Autors principals: Davis, Justin, Tjipto, Alwie, Hegerty, Katharine, Mallett, Andrew
Format: Artigo
Idioma:Inglês
Publicat: F1000 Research Limited 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854873/
https://ncbi.nlm.nih.gov/pubmed/31781368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.19997.2
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