Combined immune checkpoint blockade for metastatic uveal melanoma: a retrospective, multi-center study

BACKGROUND: Uveal melanoma (UM) is highly refractory to treatment with dismal prognosis in advanced stages. The value of the combined checkpoint blockade with CTLA-4 and PD-1 inhibition in metastatic UM is currently unclear. METHODS: Patients with metastatic or unresectable UM treated with ipilimuma...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Heppt, Markus V., Amaral, Teresa, Kähler, Katharina C., Heinzerling, Lucie, Hassel, Jessica C., Meissner, Markus, Kreuzberg, Nicole, Loquai, Carmen, Reinhardt, Lydia, Utikal, Jochen, Dabrowski, Evelyn, Gesierich, Anja, Pföhler, Claudia, Terheyden, Patrick, Thoms, Kai-Martin, Zimmer, Lisa, Eigentler, Thomas K., Kirchberger, Michael C., Stege, Henner M., Meier, Friedegund, Schlaak, Max, Berking, Carola
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854774/
https://ncbi.nlm.nih.gov/pubmed/31722735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0800-0
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