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Chlorin e6-Conjugated and PEGylated Immune Checkpoint Inhibitor Nanocomposites for Pulmonary Metastatic Colorectal Cancer

[Image: see text] Here we demonstrate theranostic immune checkpoint inhibitor nanocomposites (ICI NC) having an improved tumor targeting ability in pulmonary metastatic colon cancer model. Atezolizumab, a PD-L1 antibody, was conjugated with methoxy poly(ethylene glycol) (MePEG) and chlorin e6 (Ce6)...

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Podrobná bibliografie
Vydáno v:ACS Omega
Hlavní autoři: Jeong, Young-IL, Yoo, So Young, Heo, Jeong, Kang, Dae Hwan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2019
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854570/
https://ncbi.nlm.nih.gov/pubmed/31737818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b02386
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