Chronic elevation of endothelin-1 alone may not be sufficient to impair endothelium-dependent relaxation

Endothelin-1 (ET-1) is a powerful vasoconstrictor peptide considered to be causally implicated in hypertension and the development of cardiovascular disease. Increased ET-1 is commonly associated with reduced nitric oxide bioavailability and impaired vascular function; however, whether chronic eleva...

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Pubblicato in:Hypertension
Autori principali: Grunewald, Zachary I., Jurrissen, Thomas J., Woodford, Makenzie L., Ramirez-Perez, Francisco I., Park, Lauren K., Pettit-Mee, Ryan, Ghiarone, Thaysa, Brown, Scott M., Morales-Quinones, Mariana, Ball, James R., Staveley-O’Carroll, Kevin F., Aroor, Annayya R., Fadel, Paul J., Paradis, Pierre, Schiffrin, Ernesto L., Bender, Shawn B., Martinez-Lemus, Luis A., Padilla, Jaume
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854321/
https://ncbi.nlm.nih.gov/pubmed/31630572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13676
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