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Cell-level somatic mutation detection from single-cell RNA sequencing
MOTIVATION: Both single-cell RNA sequencing (scRNA-seq) and DNA sequencing (scDNA-seq) have been applied for cell-level genomic profiling. For mutation profiling, the latter seems more natural. However, the task is highly challenging due to the limited input materials from only two copies of DNA mol...
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| Veröffentlicht in: | Bioinformatics |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6853710/ https://ncbi.nlm.nih.gov/pubmed/31028395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz288 |
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