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Chicdiff: a computational pipeline for detecting differential chromosomal interactions in Capture Hi-C data

SUMMARY: Capture Hi-C is a powerful approach for detecting chromosomal interactions involving, at least on one end, DNA regions of interest, such as gene promoters. We present Chicdiff, an R package for robust detection of differential interactions in Capture Hi-C data. Chicdiff enhances a state-of-...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Cairns, Jonathan, Orchard, William R, Malysheva, Valeriya, Spivakov, Mikhail
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853696/
https://ncbi.nlm.nih.gov/pubmed/31197313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz450
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