LAmbDA: label ambiguous domain adaptation dataset integration reduces batch effects and improves subtype detection

MOTIVATION: Rapid advances in single cell RNA sequencing (scRNA-seq) have produced higher-resolution cellular subtypes in multiple tissues and species. Methods are increasingly needed across datasets and species to (i) remove systematic biases, (ii) model multiple datasets with ambiguous labels and...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Johnson, Travis S, Wang, Tongxin, Huang, Zhi, Yu, Christina Y, Wu, Yi, Han, Yatong, Zhang, Yan, Huang, Kun, Zhang, Jie
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
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Original Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853662/
https://ncbi.nlm.nih.gov/pubmed/31038689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz295
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