Competing endogenous RNA crosstalk at system level

microRNAs (miRNAs) regulate gene expression at post-transcriptional level by repressing target RNA molecules. Competition to bind miRNAs tends in turn to correlate their targets, establishing effective RNA-RNA interactions that can influence expression levels, buffer fluctuations and promote signal...

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Udgivet i:PLoS Comput Biol
Main Authors: Miotto, Mattia, Marinari, Enzo, De Martino, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853376/
https://ncbi.nlm.nih.gov/pubmed/31675359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007474
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