Acetyl-L-Carnitine downregulates invasion (CXCR4/CXCL12, MMP-9) and angiogenesis (VEGF, CXCL8) pathways in prostate cancer cells: rationale for prevention and interception strategies

BACKGROUND: Prostate cancer (PCa) is a leading cause of cancer-related death in males worldwide. Exacerbated inflammation and angiogenesis have been largely demonstrated to contribute to PCa progression. Diverse naturally occurring compounds and dietary supplements are endowed with anti-oxidant, ant...

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Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Baci, Denisa, Bruno, Antonino, Cascini, Caterina, Gallazzi, Matteo, Mortara, Lorenzo, Sessa, Fausto, Pelosi, Giuseppe, Albini, Adriana, Noonan, Douglas M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852951/
https://ncbi.nlm.nih.gov/pubmed/31718684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1461-z
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