Acetyl-L-Carnitine downregulates invasion (CXCR4/CXCL12, MMP-9) and angiogenesis (VEGF, CXCL8) pathways in prostate cancer cells: rationale for prevention and interception strategies

BACKGROUND: Prostate cancer (PCa) is a leading cause of cancer-related death in males worldwide. Exacerbated inflammation and angiogenesis have been largely demonstrated to contribute to PCa progression. Diverse naturally occurring compounds and dietary supplements are endowed with anti-oxidant, ant...

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Publicado en:J Exp Clin Cancer Res
Autores principales: Baci, Denisa, Bruno, Antonino, Cascini, Caterina, Gallazzi, Matteo, Mortara, Lorenzo, Sessa, Fausto, Pelosi, Giuseppe, Albini, Adriana, Noonan, Douglas M.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852951/
https://ncbi.nlm.nih.gov/pubmed/31718684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1461-z
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