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The impact of genetic background and cell lineage on the level and pattern of gene expression in position effect variegation

BACKGROUND: Chromatin-based transcriptional silencing is often described as a stochastic process, largely because of the mosaic expression observed in position effect variegation (PEV), where a euchromatic reporter gene is silenced in some cells as a consequence of juxtaposition with heterochromatin...

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Bibliografiske detaljer
Udgivet i:Epigenetics Chromatin
Main Authors: Wang, Sidney H., Elgin, Sarah C. R.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852933/
https://ncbi.nlm.nih.gov/pubmed/31722719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-019-0314-5
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