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SNP eQTL status and eQTL density in the adjacent region of the SNP are associated with its statistical significance in GWA studies

BACKGROUND: Over the relatively short history of Genome Wide Association Studies (GWASs), hundreds of GWASs have been published and thousands of disease risk-associated SNPs have been identified. Summary statistics from the conducted GWASs are often available and can be used to identify SNP features...

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Bibliografiske detaljer
Udgivet i:BMC Genet
Main Authors: Gorlov, Ivan, Xiao, Xiangjun, Mayes, Maureen, Gorlova, Olga, Amos, Christopher
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852916/
https://ncbi.nlm.nih.gov/pubmed/31718536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-019-0786-0
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