Identification of High-Affinity Small Molecule Targeting IDH2 for the Clinical Treatment of Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is symbolized by an increase in the number of myeloid cells in the bone marrow and an arrest in their maturation, frequently resulting in hematopoietic insufficiency (granulocytopenia, thrombocytopenia, or anemia) with or without leukocytosis either by a predominance of...

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Udgivet i:Asian Pac J Cancer Prev
Main Authors: Sweta, Jajoriya, Khandelwal, Ravina, Srinitha, Sivaraj, Pancholi, Rashi, Adhikary, Ritu, Ali, Meer Asif, Nayarisseri, Anuraj, Vuree, Sugunakar, Singh, Sanjeev Kumar
Format: Artigo
Sprog:Inglês
Udgivet: West Asia Organization for Cancer Prevention 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852809/
https://ncbi.nlm.nih.gov/pubmed/31450897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31557/APJCP.2019.20.8.2287
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