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Inter‐lab concordance of variant classifications establishes clinical validity of expanded carrier screening

Expanded carrier screening (ECS) panels that use next‐generation sequencing aim to identify pathogenic variants in coding and clinically relevant non‐coding regions of hundreds of genes, each associated with a serious recessive condition. ECS has established analytical validity and clinical utility,...

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Detalhes bibliográficos
Publicado no:Clin Genet
Main Authors: Kaseniit, Kristjan E., Collins, Elizabeth, Lo, Christine, Moyer, Krista, Mar‐Heyming, Rebecca, Kang, Hyunseok P., Muzzey, Dale
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852020/
https://ncbi.nlm.nih.gov/pubmed/31170325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cge.13582
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