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Effects of ketamine on circadian rhythm and synaptic homeostasis in patients with treatment‐resistant depression: A protocol for mechanistic studies of its rapid and sustained antidepressant actions in humans

BACKGROUND: The breakthrough discovery has been made that a single dose of ketamine, an N‐methyl‐D‐aspartate receptor antagonist, achieves rapid and sustained (~7 days) antidepressant activity in patients with major depressive disorder (MDD). This discovery has ushered in an exciting era of research...

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Detalhes bibliográficos
Publicado no:Brain Behav
Main Authors: Zhuo, Chuanjun, Tian, Hongjun, Li, Gongying, Chen, Min, Jiang, Deguo, Lin, Xiaodong, Xu, Yong, Wang, Wenqiang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851815/
https://ncbi.nlm.nih.gov/pubmed/31617335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.1423
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