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Hepcidin mediates hypoferremia and reduces the growth potential of bacteria in the immediate post-natal period in human neonates

Septicemia is a leading cause of death among neonates in low-income settings, a situation that is deteriorating due to high levels of antimicrobial resistance. Novel interventions are urgently needed. Iron stimulates the growth of most bacteria and hypoferremia induced by the acute phase response is...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Prentice, Sarah, Jallow, Amadou T., Sinjanka, Edrissa, Jallow, Momodou W., Sise, Ebrima A., Kessler, Noah J., Wegmuller, Rita, Cerami, Carla, Prentice, Andrew M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851364/
https://ncbi.nlm.nih.gov/pubmed/31719592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52908-w
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