Structural determinants underlying permeant discrimination of the Cx43 hemichannel

Connexin (Cx) gap junction channels comprise two hemichannels in neighboring cells, and their permeability is well-described, but permeabilities of the single Cx hemichannel remain largely unresolved. Moreover, determination of isoform-specific Cx hemichannel permeability is challenging because of c...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Nielsen, Brian Skriver, Zonta, Francesco, Farkas, Thomas, Litman, Thomas, Nielsen, Morten Schak, MacAulay, Nanna
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851295/
https://ncbi.nlm.nih.gov/pubmed/31554662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007732
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