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A GLIS3–CD133–WNT-signaling axis regulates the self-renewal of adult murine pancreatic progenitor-like cells in colonies and organoids

The existence and regenerative potential of resident stem and progenitor cells in the adult pancreas are controversial topics. A question that has been only minimally addressed is the capacity of a progenitor cell to self-renew, a key attribute that defines stem cells. Previously, our laboratory has...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tremblay, Jacob R., Lopez, Kasandra, Ku, Hsun Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851293/
https://ncbi.nlm.nih.gov/pubmed/31533988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002818
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